Basal Cell Cream
Stem cells in skin care...What does it really mean? - Repair your skin with the latest breakthrough in skin repair
Stem cells in skin care...What does it really mean? Stem cells have recently become a huge buzzword in the skincare world. But what does this really mean? Skincare specialists are not using embryonic stem cells; it is impossible to incorporate live materials into a skincare product. Instead, companies are creating products with specialized peptides and enzymes or plant stem cells which, when applied topically on the surface, help protect the human skin stem cells from damage and deterioration or stimulate the skin's own stem cells. National Stem Cell was one of the few companies who actually incorporated into their skin care an enzyme secreted from human embryonic stem cells, but they are in the process of switching over to use non-embryonic stem cells from which to take the beneficial enzyme.
Stem cells have the remarkable potential to develop into many different cell types in the body. When a stem cell divides, it can remain a stem cell or become another type of cell with a more specialized function, such as a skin cell. There are two types of stem cells, embryonic and adult.
Embryonic stem cells are exogenous in that they are harvested from outside sources, namely, fertilized human eggs. Once harvested, these pluripotent stem cells are grown in cell cultures and manipulated to generate specific cell types so they can be used to treat injury or disease.
Unlike embryonic stem cells, adult or multipotent stem cells are endogenous. They are present within our bodies and serve to maintain and repair the tissues in which they are found. Adult stem cells are found in many organs and tissues, including the skin. In fact, human skin is the largest repository of adult stem cells in the body. Skin stem cells reside in the basal layer of the epidermis where they remain dormant until they are activated by tissue injury or disease. 1
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There is controversy surrounding the use of stem cells, as some experts say that any product that claims to affect the growth of stem cells or the replication process is potentially dangerous, as it may lead to out-of-control replication or mutation. Others object to using embryonic stem cells from an ethical point of view. Some researchers believe that the use of stem cell technology for a topical, anti-aging cosmetic trivializes other, more important medical research in this field.
The skin stem cells are found near hair follicles and sweat glands and lie dormant until they "receive" signals from the body to begin the repair mode. In skincare, the use of topical products stimulates the stem cell to split into two types of cells: a new, similar stem cell and a "daughter" cell, which is able to create almost every kind of new cell in a specialized system. This means that the stem cell can receive the message to create proteins, carbohydrates and lipids to help repair fine lines, wrinkles and restore and maintain firmness and elasticity.1
To try lifecell anti-aging treatment free for 30 days visit: http://www.stem-cell-skin.creamforaging.com
Studies show that aging and damage from UV rays and pollution cause a decrease in stem-cell production. Pincelli and LVMH laboratories in 2008 identified key ingredients with the ability to protect the stem cells from external factors and produced Dior's Capture R60/80 XP In lab tests, skin samples collected from cosmetic-surgery patients showed more stem cells in the areas where cream had been applied. because it protects existing stem cells from damage, not because it increased the number of stem cells.. Says Dr. Pincelli 'That power is absolutely vital for epidermal regeneration and for maintaining the skin's youthful appearance'. 4
According to Petrikovsky, fetal skin heals in a completely different way to adult
"Adult skin heals via an inflammatory response, involving macrophages and type 1 collagen. On the other hand, fetal skin, when it is healing, relies heavily on the skin's stem cells and fibroblasts". One of the most important differences between adult and fetal skin is the fact that fetal skin heals without scarring. A wrinkle is a small wound, For this reason Petrikovsky has been looking at ways we can activate the adult stem cells in the skin to perform in similar ways to those in fetal skin. One substance he has found that can upregulate the stem cell activity of adult skin is Peptide 199, an amino acid chain derived from the Wharton Jelly, a gelatinous substance found in the umbilical cord. This upregulation ensures the fibroblast dominance over the inflammatory process during skin repair, mimicking the process that occurs in fetal skin, healing without a scar or wrinkle.5
Emerge Labs new Swiss Apple Stem Cell Serum allows plant stem cells to preserve and protect skin stem cells. PhytoCellTech - a novel plant cell culture technology has been invented to cultivate dedifferentiated callus cells from a rare Swiss apple. These apple stem cells are rich in epigenetic factors and metabolites, assuring the longevity of skin cells. The Skin Stem Cell Serum protects longevity and combats chronological aging while delaying senescence of skin cells, preserving the youthful look and vitality of one's skin.
The Institute for Biotechnological Research (IRB) has released an anti-aging ingredient based on edelweiss stem cells. "As edelweiss grows in harsh climates it is obliged to produce a number of active substances that help protect against the elements such as UV rays," IRB's Francesca Melandri says. The edelweiss active harnesses the protective substances the plant uses to defend itself against harsh climatic and environmental conditions and uses them to protect the skin,. According to the Italian company. the ingredient, Leontopodium alpinum stems, has high concentrations of leontopodic acids A and B which have strong antioxidant properties. IRB also claims the product has strong anti-collagenase and hyaluronidase actvity, therefore helping to limit the degradation of collagen and hyaluronic acid in the skin.
<!-- -->The company uses what it refers to as its HTN technology to produce the ingredients in industrial quantities. A small amount of plant biomass is chopped into tiny pieces and placed in a culture medium. Damaging the plant in this way causes the cells that surround the damage to de-differentiate (to turn back into stem cells) and form a wound healing tissue called the callus.
The callus is then harvested and grown in a cell culture medium and from this IRB obtains the plant stem cells and consequently the secondary metabolites they need for their products.
Although the technology is well known, the challenge lies in successfully scaling up the production of the stem cells to industrial quantities - a problem IRB claims to have solved with its HTN technology. 6
XTEMcell Stem Cell SkinCare has come out with its Cell Renewal Night Cream, Reset Serum, Cell Rebuilding Daytime Cream, and Repair Eye Contour Cream
According to the company, XtemCell's Patented Stem Cell Technology uses active plant cells from rare, 100% organic, nutrient-rich plants to create new cells of the highest in purity and nutrients.These new cells are able to deliver high concentrations of lipids, proteins, amino-acids and phytoalexins. They are easily absorbed into the outermost cells of the epidermis, allowing for almost immediate skin cell renewal, nutrient absorption, and an increase in the skin's level of filaggrin proteins. According to the company, "conventional plant cell extraction is only able to obtain these nutrients in smaller and far less potent quantities. Traditional plant cell cloning uses harsh chemicals or pollutants to reproduce active cells.
XTEMcell products are made from cloned stem cells from the date palm, chosen for cloning because of its unparalleled ability to live and thrive in the desert in the driest, most arid areas and be able to remain hydrated and conserve water. Xtemcell cloned these desirable properties and created a series of age-maintenance skincare products that contain 100% organic stem cells that promote a superior moisturization of the skin.
<!-- -->National Stem Cell is pursuing a different route to younger looking skin. It's subsidiary Decouverte Cosmetique is producing anti-aging products that incorporate tropelastin secreted from human embryonic stem cells. National Stem Cell changed its name to Proteonomix a month after launching a stem cell based cosmeceutical line in Aug 2008.7
The company claims the ingredient enhances the natural formation of collagen and binds with existing protein chains in the skin to make it appear smoother and firmer.
Tropelastin already affects skin appearance naturally in pregnant women. The inspiration for the products came from the natural glow of women post-conception, caused by the release of the chemical from embryonic stem cells.
The company says that the products escape the health risk warning flags out because they do not affect the growth of stem cells. However, the products formulated by Decouverte Cosmetique may be particularly controversial from an ethical or moral point of view because the active ingredient is sourced from human embryonic stem cells. However, National Stem Cell says that all the stem cells used were harvested before 2001 and none were destroyed or created in the development of the products. The company is also in the final stages of discovering how to source the key material from non-embryonic stem cells thereby weakening the ethical barrier to commercialization. 8
Thus we can see that there are already many choices in skin care products with specialized peptides and enzymes or plant stem cells which, when applied topically stimulate the skin's own stem cells. Expect many more good choices to be developed in the years to come!
To try lifecell anti-aging treatment free for 30 days visit: http://www.stem-cell-skin.creamforaging.com
References
1. Stem Cells in Skin Care...www.Creamforaging.com
2. Coleman, Claire, "Could stem cell cream be future of face care?" www.dailymail.co.uk 3/20/07
3. Ruscitton, Cynthia" Stem Cell Technology Enters the Anti-Aging Skin Care Market", ezinearticles, 4/18/07
4. Hancock, Liz, "Facing the future", www.Telegraph.co.uk., 1/11/08
5. Bird, Katie " Stem cell technology is the AaEnew age of anti-aging' skincare, say top scientists at HBA", www.Cosmeticsdesign.com 9/10/08
6. Bird, Katie, "Edelweiss stem cells could help in the fight against ageing",www.Cosmeticsdesign.com, 10/22/08
7. Montague-Jones, Guy, Biotech firm changes name after stem cell cosmetics launch", Cosmeticsdesign.com. 8/26/08
8. Montague-Jones, Guy "National Stem Cell exploits anti-aging qualities of stem cells", www.Cosmeticsdesign.com, 4/24/08
Frequently Asked Questions
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QUESTION:
Just got my first skin cancer. Basal Cell Carcinoma. Doc wants to cut it away, but why not laser? Or cream?
It's near my temple. It's about the size around of a dime or so.
I went to a derm to have it looked at. He said "yep, that's cancer" he scheduled me an appt to have it cut out. He's not a surgeon. Why should I allow him to cut into my face? I really need to know what any one else has done who was diagnosed with this on their face.-
ANSWER:
I encourage you to get a second opinion, but be sure to read up carefully on all your options first. For example, laser treatment may actually result in MORE scarring than simple surgery!If surgery ends up being your only option, ask your dermatologist to recommend a good plastic surgeon to perform the surgery, since they're better trained in surgical techniques that leave minimal scarring.
Good luck, and I hope all goes well!
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QUESTION:
Skin Cancer, basal cell and squamous cell carcinoma?
What kind of treatment is the best for basal cell carcinoma and squamous cell carcinoma? I am 30 years old, and have been diagnosed with both of these cancers and my doctor told me that we are going to talk this week about the different treatment opitions, creams, freezing and burning?? I would like to know the side effects and opitions I have, I am l eaning towards the cream, easy and I can do this at home I have small children and need to be with them. ty-
ANSWER:
I'm guessing that these are both skin cancers as squamous cell can be found elsewhere in the body.If you have been diagnosed with a squamous cell carcinoma it needs to be removed. Depending on where it is either a dermatologist/minor ops doctor or plastic suregeon will do it for you. Requires a local anaesthetic with an oval incision around the area but will be larger than the cancer to ensure all of it is removed. You will then find out the histology (someone looks down a microscope) results a few weeks later. A squamous cell carcinoma requires removal due to a very very small risk of it spreading to other organs. Takes about 10-15 minutes to remove, can go home same day.
The basal cell carcinoma has no chance of spreading. For these you can use creams and freezing. Cryotherapy or freezing is done with liquid nitrogren by the GP/dermatologist and is the same stuff used for warts/varrucas. Very quick, a little painful at the time and can go home later. You will have to have several follow up appointments until the cancer has gone away.
Alternatively you can use creams. If you have a whole area of basal cell carcinomas then you can apply a cream over the area. However be warned that certain creams are so powerful at removing cancer they will also burn your skin. You will experience a few weeks of very red painful skin over the application area but this will heal 100%. And I am repeatedly told that the skin comes back baby soft. You just have to deal with the few weeks of red skin.
And of course you can also have a basal cell carcinoma removed surgically like the squamous cell.
All these treatments shouldn't impact too mcuh on life with your kids. And if you have these two cancers then you need to keep an eye on all of your skin, particularly all of your moles. Any change in shape, colour, texture, size or if they bleed or become itchy requires a doctor to have a look at them. Now you've had these ones you are at increased risk of developing more. If increased sun exposure/UV radiation is the cause of your issues you need to watch out for malignant melanoma which is the one you don't want. But regular self-monitoring is all that is needed.
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QUESTION:
Anyone with experience in the Dermatology field or with Basal Cell Carcinoma (skin cancer)?
I am a 32 year old female with light skin, light eyes, freckles and dark hair. I had my first basal cell at 26 years old (on my chest near my collarbone) and have since had one on my face (near my hairline across from my eye) and a superficial basal cell on my eye lid (near my brow bone). The first two were removed by excision. I have yet to have the one on my eye removed because the biopsy left a large scar and I can only imagine what the scar will look like if they burn it off or if I use the cancer cream. If they burn it off I will have a huge scar there and if I use the cancer cream it will be 6-8 weeks of a nasty, festering sore. I am thinking of having the superficial basal cell excised but the nurse at the Dr's office thinks I am an idiot for not just burning the thing off. I am not overly vain but who wants a huge scar on their eye. Now, to make matters worse...I have another superficial basal cell on my eye (close to the first one) as well as a big one on my shoulder.
If you have dealt with this before...what is my best option of having the ones on my eye removed? I don't want to scar and the biopsy left a large "pock" mark which I hate and I am now faced with another one!
bmac...(love that by the way...my daughter's nickname)...basal cell is very slow growing and can kill but it takes a v e r y long time. My superficial basal cell is skin cancer but not as alarming as it sounds...it is the most common form of skin cancer. I am concerned with the scars, however. The medical staff leaves much to be desired and does not have the time nor the desire to discuss my fears at lenght. And for finding a new Dr? I can't image the next will be any better...my basal cell could kill me before I find someone who actually give a crap about some whiny lady who doesn't want a scar...I am sure you, someone who has ample experience with medical staff (having breast caner and all) would agree.-
ANSWER:
Honey, scars can be FIXED with a laser.But they can't be fixed if you're dead. Skin cancer left untreated is one of the most deadly forms of cancer.
Go get it removed right away before it spreads.
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QUESTION:
Laser removal or cut with a knife and stitch? Basal Cell Carcinoma on face? Which should I choose?
I visited a dermatologist for the first time due to concern on my face and as suspected, it's skin cancer. He didn't explain any treatment options but only told me he would do minor surgery to remove it and he drew a diagram of how the slices would go and where the scar might end up. Why do you suppose he didn't offer any other method of treatment? I am thinking he gets more $$ from the insurance company for surgery vs. cream or laser removal. I will call tomorrow to his office and ask why I wasn't notified of other available options. But I still wanted your input. Thanks!-
ANSWER:
my girlfriend has it but i don't remember her having either of those methods....ask the dr. and also look on the web for options..i think it can be frozen also...wish i could help more..so glad you got checked...
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QUESTION:
Which type of Dr. should I see to diagnose and treat my Basal Cell Carcinoma?
I had a basal cell carcinoma removed from my nose about 10 years ago. Now I have a spot on my arm that is probably basal cell as well. Up until a few days ago, I thought that I had an infected area, but now I realize that it is probably another basal cell carcinoma.I don't have health insurance, so I would like to get this diagnosed and treated as inexpensively as possible, while still fully treating the problem. When I had my first basal cell carcinoma, I had to see my doctor several times while we tried to use Fluorouracil cream. Then he sent me to a plastic surgeon who removed the cancer, but he didn't remove a big enough margin, so I had to have another surgery. So for the first skin cancer, I had the cost of several doctors visits, plus the Fluorouracil cream, plus the cost of having the surgery done on my nose twice, plus the cost of having the biopsy done twice.
This possible cancer is on my arm, so the cosmetic aspect is not quite as important as on my face, so hopefully the doctor can take a wider margin in the first place and I won't have to get the surgery done twice.
Here is my question. I am going to call a doctor tomorrow, the question is which doctor. I have three to choose from. First is my family doctor. If he looks at it and thinks it is a basal cell, he might remove it, or he might refer me. If he removes it, that would probably be my least expensive option. Or I could go to a Dermatologist. If it is a skin cancer, he might remove it, or refer me to a surgeon. If it is anything else, he would probably be the best person to treat whatever it is. Or I could go back to my plastic surgeon. I figure that with my history of basal cell, they will likely remove this if it is a basal cell or not, so why not cut out the other middlemen (doctors) and go straight the surgeon. Of course he probably won't even see me without a referral.
So my question to you is who should I go see: My family doctor, my dermatologist, or my plastic surgeon?
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ANSWER:
Your family doctor is fine. Most but not all family physicians will do minor surgery like that in the office, though he'll likely want to do the exam on one visit and then set up an appointment time for the surgery. There is, after all, the matter of managing his time in his practice.
The suggestions for an oncologist are absurd. I'm suggesting you really may have a basal cell epithelioma, as you suspect. And as you know, that's nothing in the world of cancers. Of course, it could be just a keratosis. Good luck.
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QUESTION:
Have you ever used anything to reduce a scar?
I just had some basal cell carcinoma removed and now I have a red line on my face.What I need to know is if I should buy some scar reducer cream and if so which one? Also how soon after the scar forms can I use it? Is it better to use it right away or do I need to wait?
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ANSWER:
since it from a surgery and not an accident I wouldn't fool with it until you ask the doctor when you can apply anyhing at all.
Sometimes a scar can't be removed and you just exept it and thank God the surgery was a success
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QUESTION:
Has anyone tried this out?
Marijuana oil extract as a topical cream against Basal Cell Carcinoma.Rick Simpson claims it was knocking out BCC in a little as four days.
Has anyone here tried it out?
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ANSWER:
You do not that basal cell carcinoma is the most common type of skin cancer, very slow growing, least deadly, easily treated (the doctor uses a knife to scrap my Dads off) type of cancer . . right? It is easier to just have it removed cleanly in a doctors office rather than fool around with an unknown topical cream.If you are interested in non-evidence based, untested, unverifiable cancer treatments there is a category here called Alternative Medicine where you will find people who have similar beliefs. Everyone will agree with you!
But, just for your information or for anyone else who reads this . . Cancer is an umbrella term for over 200 different types of disease . . treatment depends upon the type, location, stage (how much it has progressed) grade of tumor (how abnormal under microscope) . . treatment also considers the age of the patient ( a four year old with Neuroblastoma does not have the same treatment as an eighty year old with breast cancer), the patients overall health (if they have more than one health issue or are relatively healthy except for cancer), response to treatment (all cancer is based on our own unique DNA which means some treatment will work on one person, but not work on another based on their unique chemistry).
List of common cancer types
http://www.cancer.gov/cancertopics/alphalistIf there is efficacy using marijuana oil than Clinical Trials should be conducted by those who advocate its use to prove benefit for type of cancer or health issue, dosage , short term and long term safety, and resolve any other issues. All other drugs for use with cancer goes through the process to prove benefit, efficacy with tumor type, dosage depending on age and health of patient and how much is needed for benefit, overall safety to the patient . . . grants are available:
Clinical Trials
http://clinicaltrials.gov/
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QUESTION:
my friend is sick with headaches and dizziness and nausea?
For two weeks now, DD, has had bad headaches. She is 51, has had traumatic head injuries several years ago. So, traumatic that she is now cross-eyed. She has had headaches now and then for several years. Two weeks ago she had a headache and a nose bleed, with nausea. She has had a couple nosebleeds since then. Most of the days she has had headaches with dizziness. She says that the room would spin and she would have difficulty keeping her balance. There was no apparent fever. The other day we went to a Neurologist who was recommended by her family doctor. He tested her balance and strength. She could touch her nose with both fingers. And had arm strength. This friday she is scheduled for MRI and eeg and other tests. Two years ago she had neck surgery to replace two cervical discs. she was fine after the surgery. The doctor has her on headache meds. She is also taking meds for basal cell cancer on her nose, a cream. She just had it scraped last month. A few months ago she had a lumpectomy to remove a nonmalignant lump from her breast. Now she is on Tamoxifen 20mg.. The cancer doctor prescribed Gabapentin just recently, 300mg., for shingle like problems from her breast operation. she also takes blood pressure meds Atacand 16 mg.. She has also been under a lot of stress recently. Could these migraines be from a drug reaction plus her stress? One drug warns; may cause dizziness. The GP said that it probably may just be migraines. But l fear for her well being. She is pretty strong. But this is tough on her. Any comments?-
ANSWER:
It's sad to see people deteriorate into conditions like this but I've seen it so often among those who go into treatment processes recommended by western medicine. Most go from one thing to another and things just continue to get worse until finally they go into care 24/7 and finally succumb.Years ago I also observed that some people, like my parents who never went to doctors but treated their ailments with herbs and garden produce, lived healthy to a ripe old age, both into their 90's. So I began to study herbs, nutrition and healthy lifestyles. My, what a contrast and difference in the outcome. Now I've found a site online that actually has a system we can tap into. It's from a whole different culture and lifestyle but I believe there is much we could learn from them. Check it out.
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QUESTION:
What is the best way to dispute a missed appointment charge?
I had been told by my MD that I may have a basal cell carcinoma a few months ago. She gave me a cream to see if it was eczema. I went back to her as instructed in July. She didn't think that it was a basal cell carcinoma, wasn't sure what it was and used cryotherapy to "burn" it off. She instructed me to return in 3 weeks if it doesn't get better. It did so I did not make another appointment. Today I receive a "no show fee" for a "missed appointment" on 8/3 that I never made. What happened and how can I be held to a no show fee for an appointment that I had not scheduled?-
ANSWER:
it sounds like there was a miscommunication between the doctor and the doctor's administrative staff. for some reason, you had an appointment booked by the clerk that you didn't know about. you should call the doctor's office and ask to speak to the office manager, and explain the situation to them.
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QUESTION:
my nan has skin cancer
has it spread?
my nan has had a red mark on her forehead for quite some time (probably a year or so) and just found out she has Basal Cell skin cancer. this scares me so much
she has been given cream which she must use for 6 weeks (done 3 weeks so far) then after has to wait another 6 weeks to see the doctor again, if the cream doesnt work it must then be cut out with surgery
until then she showed me another 3 little red dots on her face, there very small but could this be more cancer? how can i tell?
also she has another red mark on her hand the size of a pea is the cancer speading???
im so scared, i dont want anything to happen to her,i love her so much,shes my life <3
please could someone tell me if there think these marks could also be skin cancer &
what else other than cancer that they could be and how can i i tell?thanks for any help
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ANSWER:
There is no way for you to tell on your own she needs to show them to her doctor that is their job. BCC is the most common cancer there is and it’s the least likely to die from. If those other spots are also cancer it is not an indication the cancer is spreading. They are new cancers. This is not unusual in people who are prone to this type of cancer.
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QUESTION:
Can eczema be removed by a dermatologist via surgery(burning/freezing)?
I have had a small patch of eczema, about the size of a dime, on my shoulder blade, for years. My last dermatologist biopsied it and we know it's eczema. He prescribed cortisone cream--which did nothing whatsoever. I don't have eczema anywhere else on my body. My question is: can small, localized patches of eczema be removed by a doctor via burning or freezing, like they do with Basal Cell Carcinomas and warts? I can't seem to find any reference to this procedure on the internet. Thanks in advance for any professional advice.-
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